Early Canadian work

LaMarche's entry into the voiceover industry was in 1980 in Easter Fever and Take Me Up to the Ball Game, two animated Canadian TV specials from Nelvana.^[14] He also was a regular voice performer on Toronto's pioneering cult TV hit The All-Night Show, which debuted in September 1980; a continuing feature had the lips of LaMarche inserted into a photograph of a famous person, and having LaMarche imitate that person to deliver a show promo or announcement. When LaMarche left the show in 1981, Jim Carrey was recruited to take his place as a voice actor.^[15]

Television

It took a few years after his 1981 move to Los Angeles for LaMarche to establish himself in the American voiceover industry, which he initially pursued as a side endeavor during his full-time standup comedy career. LaMarche began on Inspector Gadget with that show's second season in 1985, and went on to Dennis the Menace, Popeye and Son and The Real Ghostbusters where he played Egon Spengler. After The Real Ghostbusters, LaMarche became a regular mainstay of the voiceover industry, appearing in such shows as Tiny Toon Adventures, GI Joe, Attack of the Killer Tomatoes: The Animated Series, Taz-Mania, Where's Waldo, The Little Mermaid, Batman: The Animated Series, and Bonkers before landing perhaps his most recognized role in 1993 as The Brain on Animaniacs and later its spin-off show Pinky and the Brain. Following this, LaMarche worked on The Critic, Freakazoid!, and The Tick before then reprising his role of Egon in Extreme Ghostbusters. The stretch of two years after this saw LaMarche portray characters in such shows as Hey Arnold! as Big Bob Pataki, Queer Duck, and The Chimp Channel. During this time LaMarche would become the voice actor for Mortimer Mouse whom he would voice in the television series Mickey Mouse Works and House of Mouse. It was at this time, 1999, that LaMarche began work on Futurama, and since Futurama, he has continued to work steadily in television, including guest roles on The Simpsons (where he once again parodied Orson Welles). His most recent regular role came as Hovis the butler on the Nickelodeon series Catscratch. LaMarche was the voice of antagonist Father in Codename: Kids Next Door and was also the voice of Victor in Playhouse Disney's Handy Manny 2007 Halloween episode. He also played the voice role of Grumpy in the 2014 Disney XD series The 7D, a reimagining of [Snow White and the Seven Dwarfs].

LaMarche has done various voice work for many Warner Bros. Animation and DiC Entertainment cartoons. He also delivered the protracted belches for the "Great Wakkorotti" shorts on Animaniacs, in which Wakko Warner performed various pieces of music. One of those belches was later recycled for Buddy in 2003's New Line Cinema film Elf. In 2011, LaMarche reprised his role as Yosemite Sam in Cartoon Network's new series, The Looney Tunes Show, and its spin-off, New Looney Tunes.

LaMarche made several appearances in My Little Pony: Friendship Is Magic where he voiced Chancellor Neighsay.

Pinky and the Brain

LaMarche plays the character of The Brain in both Animaniacs and the spin-off.^[16] In creating the voice for Brain, LaMarche says he looked at a picture of the character and immediately thought of Orson Welles,^[17] although the character was not modeled after Welles.^[18] Voicing Brain gave LaMarche the opportunity to make use of his signature impersonation of Welles.^[19] Many Pinky and the Brain episodes are nods to Welles' career. LaMarche won an Annie Award for his role as the Brain, and was nominated for an Emmy.^[20] LaMarche would later use this accent to voice Father in Codename: Kids Next Door.

The Critic

While working on The Critic, LaMarche once voiced 29 characters in one 30-minute episode.^[21]

His time on The Critic also afforded LaMarche the opportunity to once again parody Orson Welles, this time after a video reading of a will (the Sherman family was so wealthy, they had hired Welles to narrate it) dissolves into a commercial for Mrs. Pells Fishsticks, as well as another for Rosebud Frozen Peas ("full of count-ry goodness and green pea-ness"), and another for Blotto Bros. wine. He also occasionally served as an uncredited fill-in for main cast member Jon Lovitz as Jay Sherman.

Futurama

Much of his best known voice work is from Futurama where he voiced Zapp Brannigan's beleaguered assistant Kif Kroker, melodramatic soap acting unit Calculon, the Nero-esque Hedonismbot, Morbo the news anchor, and Lrrr, ruler of the planet Omicron Persei 8, among numerous others. He has also done his Orson Welles impression on the show, winning a 2011 Outstanding Voice-Over Performance Emmy for his portrayal of Lrrr and Orson Welles in the episode "Lrrreconcilable Ndndifferences". He won another Emmy the following year for the episode "The Silence of the Clamps".

Heroes

LaMarche acted, voice only, in the second episode of the hit NBC show Heroes, "Don't Look Back", as the villain Sylar. His voice is heard in a recorded phone conversation on Chandra Suresh's answering machine. The role of Sylar was later played by Zachary Quinto.^[22]