NRK1_and_NRK2_mediated_biosynthesis_pathway_from_NR_to_NAD+.png


Summary

Description
English: NRK1/2 mediated NAD+ biosynthesis pathway from Nicotinamide riboside (NR). NR is metabolised by nicotinamide riboside kinase (NRK1/2) to form nicotinamide mononucleotide (NMN) which is then converted to nicotinamide adenine dinucleotide (NAD+) through the activity of NMN-adenylyltransferase (NMNAT). This image was created with freely available chemical structure images for NR, NMN and NADP+ from Wikimedia Commons. The chemical pathway is based on Figure 2 of https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145238/
Date
Source Own work
Author Mary Mark Ockerbloom

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Captions

NRK1/2 mediated biosynthesis pathway from NR to NAD+

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16 February 2023

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