Major_metabolic_fluxes_in_neuron-astrocyte_coupling_for_resting_conditions.png
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Description Major metabolic fluxes in neuron-astrocyte coupling for resting conditions.png |
Major metabolic fluxes (μmol/g tissue/min) in neuron-astrocyte coupling for resting conditions. The fluxes were calculated with the objective of maximizing the glutamate/glutamine/GABA cycle fluxes between the two cell types with subsequent minimization of Euclidean norm of fluxes, using the uptake rates given in Table 1 as constraints. Thick arrows show uptake and release reactions. Dashed arrows indicate shuttling of metabolites between the two cell types. Only key pathway fluxes are represented here for simplicity. The flux distributions for all the reactions listed in Additional File 1 are given in Additional File 4:Supplementary Table 3 . (Description is figure caption from original article) |
Date | |
Source | CC-by-2.0 licensed journal article: Cakir, Tunahan; Selma Alsan, Hale Saybasili, Ata Akin, Kutlu Ulgen (2007). " Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia ". Theoretical Biology and Medical Modelling 4 (1): 48. DOI : 10.1186/1742-4682-4-48 . ISSN 1742-4682 . Retrieved on 2007-12-17 . |
Author | Prepared by User:OldakQuill from diagram in journal article (see source). Authors of article: Tunahan Cakir, Selma Alsan, Hale Saybasili, Ata Akin, Kutlu Ulgen |
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Other versions | Original on page 51 of http://www.tbiomed.com/content/pdf/1742-4682-4-48.pdf |