MMAE-MAB-conjugate_skeletal.svg


Summary

Description
English: Skeletal formula of a monomethyl auristatin E (MMAE) / monoclonal antibody (MAB) conjugate. The spacer ( para -aminobenzyl carbamate ) is marked green, the cathepsin-cleavable linker (Val= valine , Cit= citrulline ) is blue, and the attachment group (consisting of maleimide and caproic acid ) is brown. The whole radical inside the four boxes is called vedotin .
Date
Source Own work
Author Anypodetos
This W3C- invalid structural formula was created with BKchem -Inkscape.

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3 November 2009