Hedgehog_signalling_copy.svg
Size of this PNG preview of this SVG file:
602 × 595 pixels
.
Other resolutions:
243 × 240 pixels
|
486 × 480 pixels
|
777 × 768 pixels
|
1,036 × 1,024 pixels
|
2,072 × 2,048 pixels
.
Summary
| Description |
English:
Suggested pathway of Smoothened(Smo) regulation via Hedgehog (Hh) and Patched (Ptch1)
When the Hedgehog protein (Hh) is not present (A.), the transmembrane Patched (Ptch1) removes oxysterols , thus preventing them from interacting with the transmembrane protein Smoothened (Smo) . When Hh is bound to Ptch1 (B.), Ptch1 no longer removes oxysterols; oxysterols accumulate and activate Smo, allowing it's signalling other cellular pathways. Inspired by diagrams created by Cyclopamine |
| Date | |
| Source | Own work |
| Author | Adenosine |
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the
Creative Commons
Attribution-Share Alike 3.0 Unported
license.
-
You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
-
Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.