DsDNA_break_repair_and_CRISPR-based_genome_editing.svg


Summary

Description
English: On the left a flowchart showing the different DNA repair pathways [1] that may act on a double-stranded DNA break , together with their typical outcome. Annotations in light gray indicate the proteins or processes that facilitate progress to the next step in the flowchart. On the right an illustration how these properties of DNA repair can be used in CRISPR-based genome editing .
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Author J.J.Froehlich
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Attribution: J.J.Froehlich
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  1. Yeh, Charles D.; Richardson, Christopher D.; Corn, Jacob E. (2019), “Advances in genome editing through control of DNA repair pathways”, in Nature Cell Biology [1] , Springer Nature

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dsDNA-break repair and CRISPR-based genome editing

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29 August 2022

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