DHFR_methotrexate_inhibitor.png


Summary

Description
English: An enzyme binding site that would normally bind substrate can alternatively bind a competitive inhibitor , preventing substrate access. Dihydrofolate reductase is inhibited by methotrexate which prevents binding of its substrate, folic acid . Binding site in blue, inhibitor in green, and substrate in black. ( PDB : 4QI9 ​)
Date
Source Own work
Author Thomas Shafee
Other versions For vector version, see File:DHFR methotrexate inhibitor.svg

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6 March 2015

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