This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by Ostrov et al. in 2000. I rendered the image in PyMol myself based on the published pdb file.

For the published pdb, please see: Ostrov, D.A., Shi, W., Schwartz, J.C., Almo, S.C., Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science v290 pp.816-819 , 2000.

Description CTLA4 Crystal Structure.rsh.png	Crystal structure of CTLA4 as published in the Protein Data Bank (PDB: 1DQT)
Date	12 October 2006
Source	Created from PDB 1DQT and rendered by me using Pymol
Author	Ramin Herati
Permission ( Reusing this file )	Public domain Public domain false false I, the copyright holder of this work, release this work into the public domain . This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose , without any conditions, unless such conditions are required by law.