Binary_BCF_versus_VCF_format.png
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Summary
| Description |
English:
BCF, the binary representation of the VCF format, is much faster to process than VCF for two reasons. First, it avoids the expensive conversion from text to the internal binary representation. Second, the fields in BCF are rearranged to allow rapid access to specific value of any sample. This is achieved by storing values in blocks of the same type rather than per-sample, with offsets to blocks determined on the fly.
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| Date | |
| Source | HTSlib: C library for reading/writing high-throughput sequencing data, GigaScience, Volume 10, Issue 2, February 2021, giab007, (see the supplemental files, all published open access0. https://doi.org/10.1093/gigascience/giab007 and https://academic.oup.com/gigascience/article/10/2/giab007/6139334?searchresult=1 |
| Author | James K Bonfield, John Marshall, Petr Danecek, Heng Li, Valeriu Ohan, Andrew Whitwham, Thomas Keane, Robert M Davies |
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