Beta2Receptor-with-Gs.png
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| Description |
English:
Crystal structure of activated beta-2 adrenergic receptor in complex with G
s
. The receptor is colored red, Gα green, Gβ cyan and Gγ yellow. T4 Lysozyme and nanobody, which were used to facilitate crystallization, are omitted for clarity. Note that the C-terminus of Gα is located in a cavity created by an outward movement of the cytoplasmic parts of TM5 and 6. Rendered from
PDB
entry
3SN6
.
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| Date | |||
| Source |
From
PDB
entry
3SN6
.
Reference: Søren G. F. Rasmussen, Brian T. DeVree, Yaozhong Zou, Andrew C. Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski, Jesper M. Mathiesen, Syed T. A. Shah, Joseph A. Lyons, Martin Caffrey, Samuel H. Gellman, Jan Steyaert, Georgios Skiniotis, William I. Weis, Roger K. Sunahara, Brian K. Kobilka (July 2011). "Crystal structure of the beta(2) adrenergic receptor-Gs protein complex". Nature . DOI : 10.1038/nature10361 . PMID 21772288 . |
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| Author | Nakane | ||
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Permission
( Reusing this file ) |
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| Other versions | File:3sn6 G-coupled ribbon.png |
