Amlodipine_and_major_metabolite.svg
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Summary
Description Amlodipine and major metabolite.svg |
English:
Amlodipine and one of its major metabolites. The amine group is oxidated and the side ester chains are hydrolyzed.
Español:
Amlodipino y uno de sus metabolitos principales. El se oxida el grupo amino y se hidrolizan los grupos de éster.
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Date | |
Source | Own work |
Author | Persia Salehi |
References:
- Zhu, Yanlin; Wang, Fen; Li, Quan; Zhu, Mingshe; Du, Alicia; Tang, Wei; Chen, Weighing (2014). " Amlodipine Metabolism in Human Liver Microsomes and Roles of CYP3A4/5 in the Dihydropyridine Dehydrogenation ". Drug Metabolism and Disposition 42 (2): 245-249. DOI : 10.1124/dmd.113.055400 . PMID 24301608 . ISSN 0090-9556 .
Made using the
chemfig
package in LaTex.
\documentclass[10pt]{article} \usepackage{chemfig} \setdoublesep{0.091 cm} % Bond Spacing \setatomsep{14.4 pt} % Bond length \setcrambond{2 pt}{1 pt}{2.5 pt} % {Bold width}{1pt}{Hash spacing} \setbondoffset{1.6 pt} % Margin Width \setbondstyle{line width=0.6 pt} % Line width \renewcommand*\printatom[1]{\normalsize \ensuremath{\mathsf{#1}}} \begin{document} \schemestart \chemfig{ -[:90]O -[:30] (=[:90,0.75]O) -[:-30] *6( = (-[:210]) -\chembelow{N}{H} - (-[:-30] -[:30]O -[:-30] -[:30] -[:-30]NH_2 ) = ( -[:30](=[:90,0.75]O) -[:-30]O -[:30] ) - ( -[:90,1.5] *6( - (-[,.75]Cl) = - = - = ) ) - ) } \arrow{->} \hspace{0.7 cm} \chemfig{ -[:90]O -[:30] (=[:90,0.75]O) -[:-30] *6( =[,,,,magenta] (-[:210]) -[,,,,magenta]\color{magenta}{N} =[,,,,magenta] (-[:-30] -[:30]\color{magenta}{OH} ) -[,,,,magenta] ( -[:30](=[:90,0.75]O) -[:-30]\color{magenta}{OH} ) =[,,,,magenta] ( -[:90,1.5] *6( - (-[,.75]Cl) = - = - = ) ) -[,,,,magenta] ) } \schemestop \end{document}
Licensing
Public domain Public domain false false |
This image of a simple structural formula is ineligible for copyright and therefore in the public domain , because it consists entirely of information that is common property and contains no original authorship. |