A_summary_of_functional_annotation_of_the_most_ancestral_translation_protein_folds.svg
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Summary
Description A summary of functional annotation of the most ancestral translation protein folds.svg |
English:
Nine of the ten most ancestral folds identified by Wang et al. [26] are present in translation proteins. The specific functional roles of these folds converge on four general categories: high energy phos- phoryl transfer, RNA modification, RNA binding, and protein binding. Exceptions are aminoacylation by tRNA synthetase and tRNA splicing by ribo- somal protein S28e. Taken together, the functions imparted by these nine most ancestral folds represent all of the central protein functions in the modern translation system (Figure 4). A summary of the genes in which these folds are found is available as Additional file 2. A detailed annotation of functions imparted by these folds is available as Additional file 3.
[1]
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Date | |
Source | doi: 10.1186/1745-6150-5-15 |
Author | Aaron D Goldman, Ram Samudrala and John A Baross |
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