Route 21 is a highway in eastern Missouri. Its northern terminus is at Route 30 in Affton. Its southern terminus is at the Arkansas state line (where it continues as Highway 115). In the St. Louis area, it is known as Tesson Ferry Road, which was named after the 19th century proprietor of the ferry across the Meramec River.

Quick Facts Route 21, Route information ...

Route 21
Tesson Ferry Road
Route information
Maintained by MoDOT
Length	188 mi (303 km)
Existed	1922–present
Major junctions
South end	AR 115 at the Arkansas state line
Major intersections	US 160 in Doniphan US 60 near Van Buren Route 72 in Centerville Route 49 in Hogan Route 32 in Caledonia Route 47 in Mineral Point Route M / Route MM in Barnhart Route 141 in Paulina Hills I-270 in Concord US 50 / US 61 / US 67 in Concord
North end	Route 30 in Affton
Location
Country	United States
State	Missouri
Counties	Ripley, Carter, Reynolds, Iron, Washington, Jefferson, St. Louis
Highway system
Missouri State Highway System Interstate US State Supplemental
← Route 20 → Route 22

Close

The section through northern Jefferson County, Missouri was considered dangerous. As a result, the road was rerouted and built to freeway standards. Construction to reroute the highway to just south of Hillsboro was completed on December 15, 2008 and Route 21 is currently freeway standard from Route 141 to Highway B. Plans to extend the freeway south to DeSoto have been approved, but funds are lacking to complete this part of the project.^[1]

Route 21 from the Meramec River to Route B, along with Route M, make up the Jefferson County Scenic Byway.^[2][3]

Business 21 follows the old alignment of Route 21 through the city of Hillsboro. It begins at the intersection of Route 21 and Highway B on the southern edge of the city, and continues north to the intersection of Route A and Old Route 21, where it ends. Business 21 is the only way one can now reach Route BB, as the rerouting of Route 21 bypasses the road.

• List of state highways in Missouri
• List of highways numbered 21