The year 2000 in film involved some significant events. The top grosser worldwide was Mission: Impossible 2.^[1] Domestically in North America, Gladiator won the Academy Awards for Best Picture and Best Actor (Russell Crowe).^[2] Dinosaur was the most expensive film of 2000 and a box-office success.^[1]

The top 10 films released in 2000 by worldwide gross are as follows:^[3][4]

• January 7 – Marcus Scribner, American actor
• January 8 – Noah Cyrus, American actress and singer
• January 9 – Gordon Maeda, Japanese actor
• January 10 – Reneé Rapp, American actress and singer
• January 11 – Jamie Bick, German actress
• January 17 – Chani, South Korean actor
• January 19 – Asahi Ito, Japanese actor
• January 21 – Eito Konishi, Japanese actor
• January 26 – Ester Expósito, Spanish actress
• January 28 – Julia Lester, American actress
• January 30
  • Markella Kavenagh, Australian actress
  • Frida Argento, Swedish actress
• February 5
  • Esmé Creed-Miles, English actress
  • Jordan Nagai, American former child voice actor
• February 9 – Evan Roe, American actor
• February 10 – Yara Shahidi, American actress
• February 12 – Asuka Kawazu, Japanese actress
• February 22 – Celia Rose Gooding, American actress and singer
• February 23 – Christian Martyn, Canadian actor
• February 25
  • Tucker Albrizzi, American actor
  • Laura Ann Kesling, American actress
• February 27 – Tsuyoshi Furukawa, Japanese singer and actor
• February 28 – Jonathan Daviss, American actor

March 5 – Reiky de Valk, Dutch actor (d. 2023)

• March 6 – Jacob Bertrand, American actor
• March 21 – Jace Norman, American actor
• March 22
  • Pawat Chittsawangdee, Thai actor
  • Zoe Terakes, Australian actor
• March 27
  • Halle Bailey, American actress
  • Sophie Nélisse, Canadian actress
• March 31 – Ruby Cruz, American actress
• April 9 – Brenock O'Connor, English actor
• April 11
  • Milly Alcock, Australian actress
  • Morgan Lily, American actress and model
• April 13 – Suzanne Lindon, French actress and filmmaker
• April 16 – Bruna Carvalho, Brazilian actress
• April 20 – Abigail Duhon, American Christian musician and actress
• April 22 – Billy Price, English actor
• May 4 – Nicholas Hamilton, Australian actor
• May 7 – Maxwell Perry Cotton, American actor
• May 13 – Antonio Cipriano, American actor
• May 18 – Addison Holley, Canadian actress
• May 23 – Ella Rappich, Swedish actress born in South Africa
• May 30 – Jared S. Gilmore, American actor
• June 1 – Willow Shields, American actress
• June 13 – Daniella Perkins, American actress
• June 14 – Thomaz Costa, Brazilian actor
• June 15 – Ouyang Nana, Taiwanese actress, singer and musician
• June 17 – Odessa A'zion, American actress
• June 23
  • Kim Hyunsoo, South Korean actress
  • Earl Cave, English actor
  • Caitlin Blackwood, Scottish actress
• June 25 – Iman Benson, American actress
• July 8 – Benjamin Stockham, American actor
• July 9 – Courtney Grosbeck, American actress and model
• July 13
  • Lucas Lynggaard Tønnesen, Danish actor
  • Malia Pyles, American actress
• July 14 – Maia Reficco, American actress and singer
• July 15 – Julio Peña Fernández, Spanish actor
• July 16 – Jonathan Morgan Heit, American actor
• July 17 – Nico Liersch, German actor
• July 19 – Owen Joyner, American actor
• July 22 – Kaori Oinuma, Filipino-Japanese actress and model
• July 23 – Malte Gårdinger, Swedish actor
• July 25
  • Meg Donnelly, American actress
  • Preston Bailey, American Actor
• July 26 – Thomasin McKenzie, New Zealand actress
• July 29 – Lino Facioli, Brazilian actor
• July 31 – Kim Sae-ron, South Korean actress
• August 3 – Landry Bender, American actress
• August 9 – Kim Hyang-gi, South Korean actress
• August 16 – Lacey Dover, American actress
• August 20 – Fátima Ptacek, American actress and activist
• August 24 – Griffin Gluck, American actor
• August 29 – Minami Hamabe, Japanese actress
• August 31 – Mia Jenkins, English actress
• September 3 – Ashley Boettcher, American actress
• September 4 – Ruby Stokes, English actress
• September 11 – Grayson Maxwell Gurnsey, Canadian actor
• September 12 – Becky Zhu Wu, Mexican actress
• September 13 – Siddharth Nigam, Indian actor
• September 14 – Ritvik Sahore, Indian actor
• September 15 – Mallika Singh, Indian actress
• September 22 – Michael Rainey Jr., American actor
• September 23 – Kalani Hilliker, American dancer and actress
• September 25 – Anna Lambe, Canadian Inuk actress from Iqaluit, Nunavut
• September 28 – Frankie Jonas, American actor
• October 6
  • Klara Castanho, Brazilian actress
  • Addison Rae, American social media personality and actress
  • Isobelle Molloy, English actress
• October 10 – Aedin Mincks, American actor
• October 14 – Mekai Curtis, American actor
• October 18
  • Sophie Thatcher, American actress
  • Conor Sherry, American actor
• October 26 – Ellery Sprayberry, American actress and voice
• October 27 – Lucie Zhang, French actress
• October 31 – Willow Smith, American singer and actress
• November 7 – Dara Reneé, American actress
• November 8 – Jade Pettyjohn, American actress
• November 10 – Mackenzie Foy, American model and actress
• November 18 – Arabella Morton, Australian actress
• November 22 – Auliʻi Cravalho, American actress and singer
• November 28
  • Jackson Yee, Chinese actor and singer
  • Kaitlyn Bernard, Canadian actress
• December 9 – Jaren Lewison, American actor
• December 12
  • Devyn Nekoda, Canadian actress
  • Lucas Jade Zumann, American actor
• December 16
  • Rachelle Henry, American actress and filmmaker
  • Lance Lim, American actor
• December 18 – Korapat Kirdpan, Thai actor
• December 19 – Yuumi Kawai, Japanese actress
• December 28 – Larissa Manoela, Brazilian actress
• Thomas Weatherall, Australian actor

• List of 2000 box office number-one films in the United States