Wd_repeat_containing_planar_cell_polarity_effector

Wd repeat containing planar cell polarity effector

Wd repeat containing planar cell polarity effector

Protein-coding gene in the species Homo sapiens

WD repeat containing planar cell polarity effector is a protein that in humans is encoded by the WDPCP gene. [5]

Quick Facts WDPCP, Identifiers ...

Function

This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternative splicing results in multiple transcript variants.

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000143951 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000020319 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: WD repeat containing planar cell polarity effector". Retrieved 2017-06-07.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Stub icon

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.
Share this article:

This article uses material from the Wikipedia article Wd_repeat_containing_planar_cell_polarity_effector, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.