WNT8B

WNT8B

WNT8B

Protein-coding gene in humans

Protein Wnt-8b is a protein that in humans is encoded by the WNT8B gene.[5][6]

Quick Facts Identifiers, Aliases ...

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.

This gene is a member of the WNT gene family. It encodes a protein showing 95%, 86%, and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.[6]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000075290 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000036961 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Lako M, Strachan T, Curtis AR, Lindsay S (Sep 1996). "Isolation and characterization of WNT8B, a novel human Wnt gene that maps to 10q24". Genomics. 35 (2): 386–8. doi:10.1006/geno.1996.0374. PMID 8661156.
  6. [6]
    "Entrez Gene: WNT8B wingless-type MMTV integration site family, member 8B".

Further reading



Stub icon

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.
Share this article:

This article uses material from the Wikipedia article WNT8B, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.