WNT5B

WNT5B

WNT5B

Protein-coding gene in the species Homo sapiens

Protein Wnt-5b is a protein that in humans is encoded by the WNT5B gene.[5][6]

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The WNT gene family consists of structurally-related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates two transcript variants.[6]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000111186 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000030170 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Saitoh T, Katoh M (Jul 2001). "Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region". Int J Oncol. 19 (2): 347–51. doi:10.3892/ijo.19.2.347. PMID 11445850.
  6. [6]
    "Entrez Gene: WNT5B wingless-type MMTV integration site family, member 5B".

Further reading



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