VUF-5681 is a potent and selective histamine antagonist which binds selectively to the H₃ subtype.^[1] However while VUF-5681 blocks the activity of more potent H₃ agonists, recent studies suggest that it may have some weak partial agonist activity when administered by itself.^[2]

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VUF-5681

Names
Preferred IUPAC name 4-[3-(1H-Imidazol-5-yl)propyl]piperidine
Identifiers
CAS Number	768358-61-8 Y
3D model (JSmol)	Interactive image
ChemSpider	8505701 N
PubChem CID	10330240
UNII	WR5V5TB2TR Y
CompTox Dashboard (EPA)	DTXSID501277310
InChI InChI=1S/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14) N Key: YPGRNKJNOSUCLY-UHFFFAOYSA-N N InChI=1/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14) Key: YPGRNKJNOSUCLY-UHFFFAOYAZ
SMILES C1CNCCC1CCCC2=CN=CN2
Properties
Chemical formula	C11H19N3
Molar mass	193.288 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

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