VSIG1

VSIG1

VSIG1

Protein-coding gene in the species Homo sapiens

V-set and immunoglobulin domain containing 1 is a protein that in humans is encoded by the VSIG1 gene.[5]

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Function

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in a normal stomach and testis, as well as in gastric, esophageal, and ovarian cancers. Alternatively spliced transcript variants, encoding different isoforms, have been found for this gene. [provided by RefSeq, Dec 2009].

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000101842 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000031430 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: V-set and immunoglobulin domain containing 1". Retrieved 2018-09-09.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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