VN1R1
VN1R1
Protein-coding gene in the species Homo sapiens
Vomeronasal type-1 receptor 1 is a protein that in humans is encoded by the VN1R1 gene.[3][4]
Quick Facts Identifiers, Aliases ...
| VN1R1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | VN1R1, V1RL1, VNR19I1, ZVNH1, ZVNR1, vomeronasal 1 receptor 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 605234 HomoloGene: 110801 GeneCards: VN1R1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Pheromones are chemical signals that elicit specific behavioral responses and physiologic alterations in recipients of the same species. The protein encoded by this gene is similar to pheromone receptors and is primarily localized to the olfactory mucosa. An alternate splice variant of this gene is thought to exist, but its full length nature has not been determined.[4]
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Shirokova E, Raguse JD, Meyerhof W, Krautwurst D. The human vomeronasal type-1 receptor family--detection of volatiles and cAMP signaling in HeLa/Olf cells. FASEB J. 2008 May;22(5):1416-25. doi:10.1096/fj.07-9233com PMID 18096815
- Ouyang J, Bae H, Jordi S, Dao QM, Dossenbach S, Dehn S, Lingnau JB, Kanta De C, Kraft P, List B (Feb 2021). "The Smelling Principle of Vetiver Oil, Unveiled by Chemical Synthesis". Angew Chem Int Ed Engl. 60 (11): 5666–5672. doi:10.1002/anie.202014609. PMC 7986879. PMID 33315304. (reference 30)
- Giorgi D, Friedman C, Trask BJ, Rouquier S (December 2000). "Characterization of nonfunctional V1R-like pheromone receptor sequences in human". Genome Research. 10 (12): 1979–85. doi:10.1101/gr.10.12.1979. PMC 313059. PMID 11116092.
- Pantages E, Dulac C (December 2000). "A novel family of candidate pheromone receptors in mammals". Neuron. 28 (3): 835–45. doi:10.1016/S0896-6273(00)00157-4. PMID 11163270. S2CID 15023062.
- Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S (June 2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Letters. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
- Zhang J, Webb DM (July 2003). "Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates". Proceedings of the National Academy of Sciences of the United States of America. 100 (14): 8337–41. Bibcode:2003PNAS..100.8337Z. doi:10.1073/pnas.1331721100. PMC 166230. PMID 12826614.
- Mitropoulos C, Papachatzopoulou A, Menounos PG, Kolonelou C, Pappa M, Bertolis G, Gerou S, Patrinos GP (2007). "Association study of human VN1R1 pheromone receptor gene alleles and gender". Genetic Testing. 11 (2): 128–32. doi:10.1089/gte.2006.0516. PMID 17627382.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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