Uldazepam

Uldazepam

Uldazepam

Chemical compound

Uldazepam is a drug which is a benzodiazepine derivative.[1] It has sedative and anxiolytic effects similar to those of other benzodiazepines.[2][3]

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Synthesis

Thio thionamide is even more prone to amidine formation than the lactam itself.

Uldazepam synthesis:[4] J. B. Hester, Jr., (1970); Chem. Abstr., 73: 99,001t (1970).

Reaction of thionamide (2) with O-allyl-hydroxylamine gave the oximino (3) uldazepam.

See also

References

  1. [1]
    "Uldazepam U 31920". Psychotropics. Retrieved 12 June 2013.
  2. [2]
    Oelschläger H, Ellaithy MM, Volke J (February 1988). "[Mechanism of the polarographic reduction of the tranquilizer uldazepam]". Archiv der Pharmazie (in German). 321 (2): 69–72. doi:10.1002/ardp.19883210205. PMID 3369929. S2CID 96356746.
  3. [3]
    Itil TM, Akpinar S, Ozkut H, Balki N, Herrmann WM (June 1974). "Clinical and computerized EEG effects of U-31,920, a new anxiolytic". Current Therapeutic Research, Clinical and Experimental. 16 (6): 642–54. PMID 4211146.
  4. [4]
    DE 2005176, Hester Jr., Jackson Boling, "3H-1,4-benzodiazepine und Verfahren zu deren Herstellung [3H-1,4-benzodiazepines and processes for their preparation]", published 1970-09-10, assigned to The Upjohn Co.
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