UDP-N-acetyl-D-mannosamine_dehydrogenase

UDP-N-acetyl-D-mannosamine dehydrogenase

UDP-N-acetyl-D-mannosamine dehydrogenase

Class of enzymes

UDP-N-acetyl-D-mannosamine dehydrogenase (EC 1.1.1.336, UDP-ManNAc 6-dehydrogenase, wecC (gene)) is an enzyme with systematic name UDP-N-acetyl-alpha-D-mannosamine:NAD+ 6-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+
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This enzyme participates in acetamido sugar biosynthesis in bacteria and archaea.

References

  1. [1]
    Namboori SC, Graham DE (April 2008). "Acetamido sugar biosynthesis in the Euryarchaea". Journal of Bacteriology. 190 (8): 2987–96. doi:10.1128/JB.01970-07. PMC 2293230. PMID 18263721.
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