Template:Relative_affinities_of_anabolic_steroids_and_related_steroids

Template:Relative affinities of anabolic steroids and related steroids

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Relative affinities of anabolic steroids and related steroids
Steroid	Chemical name	Relative binding affinities (%)
Steroid	Chemical name	PRTooltip Progesterone receptor	ARTooltip Androgen receptor	ERTooltip Estrogen receptor	GRTooltip Glucocorticoid receptor	MRTooltip Mineralocorticoid receptor	SHBGTooltip Sex hormone-binding globulin	CBGTooltip Corticosteroid-binding globulin
Androstanolone	DHT	1.4–1.5	60–120	<0.1	<0.1–0.3	0.15	100	0.8
Boldenone	Δ¹-T	<1	50–75	?	<1	?	?	?
Danazol	2,3-Isoxazol-17α-Ety-T	9	8	?	<0.1^a	?	8	10
Dienolone	∆⁹-19-NT	17	134	<0.1	1.6	0.3	?	?
Dimethyldienolone	∆⁹-7α,17α-DiMe-19-NT	198	122	0.1	6.1	1.7	?	?
Dimethyltrienolone	∆^9,11-7α,17α-DiMe-19-NT	306	180	0.1	22	52	?	?
Drostanolone	2α-Me-DHT	?	?	?	?	?	39	?
Ethisterone	17α-Ety-T	35	0.1	<1.0	<1.0	<1.0	25–92	0.3
Ethylestrenol	3-DeO-17α-Et-19-NT	?	?	?	?	?	<1	?
Fluoxymesterone	9α-F-11β-OH-17α-Me-T	?	?	?	?	?	≤3	?
Gestrinone	∆^9,11-17α-Ety-18-Me-19-NT	75–76	83–85	<0.1–10	77	3.2	?	?
Levonorgestrel	17α-Ety-18-Me-19-NT	170	84–87	<0.1	14	0.6–0.9	14–50	<0.1
Mestanolone	17α-Me-DHT	5–10	100–125	?	<1	?	84	?
Mesterolone	1α-Me-DHT	?	?	?	?	?	82–440	?
Metandienone	∆¹-17α-Me-T	?	?	?	?	?	2	?
Metenolone	∆¹-1-Me-DHT	?	?	?	?	?	3	?
Methandriol	17α-Me-A5	?	?	?	?	?	40	?
Methasterone	2α,17α-DiMe-DHT	?	?	?	?	?	58	?
Methyldienolone	∆⁹-17α-Me-19-NT	71	64	<0.1	6	0.4	?	?
Methyltestosterone	17α-Me-T	3	45–125	<0.1	1–5	?	5–64	<0.1
Methyl-1-testosterone	∆¹-17α-Me-DHT	?	?	?	?	?	69	?
Metribolone	∆^9,11-17α-Me-19-NT	208–210	199–210	<0.1	10–26	18	0.2–0.8	≤0.4
Mibolerone	7α,17α-DiMe-19-NT	214	108	<0.1	1.4	2.1	6	?
Nandrolone	19-NT	20	154–155	<0.1	0.5	1.6	1–16	0.1
Norethandrolone	17α-Et-19-NT	?	?	?	?	?	3	?
Norethisterone	17α-Ety-19-NT	155–156	43–45	<0.1	2.7–2.8	0.2	5–21	0.3
Norgestrienone	∆^9,11-17α-Ety-19-NT	63–65	70	<0.1	11	1.8	?	?
Normethandrone	17α-Me-19-NT	100	146	<0.1	1.5	0.6	7	?
Oxandrolone	2-Oxa-17α-Me-DHT	?	?	?	?	?	<1	?
Oxymetholone	2-OHMeEne-17α-Me-DHT	?	?	?	?	?	≤3	?
RU-2309 (17α-Me-THG)	∆^9,11-17α,18-DiMe-19-NT	230	143	<0.1	155	36	?	?
Stanozolol	2,3-Pyrazol-17α-Me-DHT	?	?	?	?	?	1–36	?
Testosterone	T	1.0–1.2	100	<0.1	0.17	0.9	19–82	3–8
1-Testosterone	∆¹-DHT	?	?	?	?	?	98	?
Tibolone	7α-Me-17α-Ety-19-N-5(10)-T	12	12	1	?	?	?	?
Δ⁴-Tibolone	7α-Me-17α-Ety-19-NT	180	70	1	<1	2	1–8	<1
Trenbolone	∆^9,11-19-NT	74–75	190–197	<0.1	2.9	1.33	?	?
Trestolone	7α-Me-19-NT	50–75	100–125	?	<1	?	12	?
Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PRTooltip progesterone receptor, testosterone for the ARTooltip androgen receptor, estradiol for the ERTooltip estrogen receptor, dexamethasone for the GRTooltip glucocorticoid receptor, aldosterone for the MRTooltip mineralocorticoid receptor, dihydrotestosterone for SHBGTooltip sex hormone-binding globulin, and cortisol for CBGTooltip corticosteroid-binding globulin. Footnotes: ^a = 1-hour incubation time (4 hours is standard for this assay; may affect affinity value). Sources: ^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]^[9]^[10]

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Template:Relative_affinities_of_anabolic_steroids_and_related_steroids

Template:Relative affinities of anabolic steroids and related steroids

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