Template:Methadone_at_opioid_receptors,_monoamine_transporters,_and_the_NMDA_receptor

Template:Methadone at opioid receptors, monoamine transporters, and the NMDA receptor

More information Compound, Affinities (KiTooltip Inhibitor constant, in nM) ...

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Compound	Affinities (K_iTooltip Inhibitor constant, in nM)						Ratios
Compound	MORTooltip μ-Opioid receptor	DORTooltip δ-Opioid receptor	KORTooltip κ-Opioid receptor	SERTTooltip Serotonin transporter	NETTooltip Norepinephrine transporter	NMDARTooltip N-Methyl-D-aspartate receptor	M:D:K	SERT:NET
Racemic methadone	1.7	435	405	1,400	259	2,500–8,300	1:256:238	1:5
Dextromethadone	19.7	960	1,370	992	12,700	2,600–7,400	1:49:70	1:13
Levomethadone	0.945	371	1,860	14.1	702	2,800–3,400	1:393:1968	1:50

References