TH-PVP
TH-PVP
Chemical compound
TH-PVP is a substituted cathinone derivative which has been sold as a designer drug. It was first identified by a forensic laboratory in Hungary in 2015,[2] but has subsequently been found in numerous other countries around the world including Spain, Belgium, Poland, Turkey and Brazil.[3][4][5][6][7][8] Pharmacological studies in vitro showed it to inhibit reuptake and promote the release of monoamine neurotransmitters with some selectivity for serotonin,[9] but it failed to produce stimulant effects in animals,[10] and has a pharmacological profile more comparable to that of sedating empathogens such as MDAI and 5-Methyl-MDA.