TAS2R50

TAS2R50

TAS2R50

Protein-coding gene in the species Homo sapiens

Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.[5][6][7][8]

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Function

TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.[6] See also TAS2R10.[8]

See also

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000212126 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000053217 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
  6. [6]
    Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
  7. [7]
    Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP (Sep 2005). "Identification of Four Gene Variants Associated with Myocardial Infarction". Am J Hum Genet. 77 (4): 596–605. doi:10.1086/491674. PMC 1275608. PMID 16175505.
  8. [8]
    "Entrez Gene: TAS2R50 taste receptor, type 2, member 50".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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