TAF3

TAF3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5C13
Identifiers
Aliases	TAF3, TAF140, TAFII-140, TAFII140, TATA-box binding protein associated factor 3
External IDs	OMIM: 606576; MGI: 2388097; HomoloGene: 35415; GeneCards: TAF3; OMA:TAF3 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	8,016,631 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	10,053,407 bp
RNA expression pattern
	Top expressed in
	vena cava; ; oocyte; ; cardia; ; sural nerve; ; secondary oocyte; ; internal globus pallidus; ; pylorus; ; pericardium; ; ventral tegmental area; ; sperm;
	Top expressed in
	secondary oocyte; ; otolith organ; ; utricle; ; substantia nigra; ; hand; ; retinal pigment epithelium; ; medullary collecting duct; ; yolk sac; ; aortic valve; ; cumulus cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	p53 binding; protein binding; metal ion binding; protein heterodimerization activity;
Cellular component	nucleus; nucleoplasm; nuclear membrane; transcription factor TFIID complex;
Biological process	transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; negative regulation of DNA-binding transcription factor activity; maintenance of protein location in nucleus; transcription, DNA-templated; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	83860
	209361
	ENSG00000165632
	ENSMUSG00000025782
	Q5VWG9
	Q5HZG4
	NM_031923
	NM_027748
	NP_114129
	NP_082024
	Wikidata
View/Edit Human	View/Edit Mouse

TAF3

Protein-coding gene in the species Homo sapiens

Transcription initiation factor TFIID subunit 3 is a protein that in humans is encoded by the TAF3 gene.^[5]^[6]^[7]

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This article uses material from the Wikipedia article TAF3, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000165632 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000025782 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11438666-5] [5]
Gangloff YG, Pointud JC, Thuault S, Carre L, Romier C, Muratoglu S, Brand M, Tora L, Couderc JL, Davidson I (Jul 2001). "The TFIID Components Human TAFII140 and Drosophila BIP2 (TAFII155) Are Novel Metazoan Homologues of Yeast TAFII47 Containing a Histone Fold and a PHD Finger". Mol Cell Biol. 21 (15): 5109–21. doi:10.1128/MCB.21.15.5109-5121.2001. PMC 87236. PMID 11438666.

[pmid18549481-6] [6]
Bereczki O, Ujfaludi Z, Pardi N, Nagy Z, Tora L, Boros IM, Balint E (Jun 2008). "TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function". BMC Mol Biol. 9: 57. doi:10.1186/1471-2199-9-57. PMC 2441632. PMID 18549481.

[entrez-7] [7]
"Entrez Gene: TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa".

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[6]

[7]

[1]

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[3]

[4]

TAF3

TAF3

References

Further reading

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