Steven_E._Brenner
Steven Elliot Brenner is a professor at the Department of Plant and Microbial Biology at the University of California Berkeley, adjunct professor at the Department of Bioengineering and Therapeutic Sciences at the University of California, and San Francisco Faculty scientist, Physical Biosciences at the Lawrence Berkeley National Laboratory.[2][3][4]
Steven Brenner | |
|---|---|
Steven E. Brenner speaking at the ISMB conference in 2015. | |
| Born | Steven Elliot Brenner |
| Alma mater |
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| Known for | Structural Classification of Proteins |
| Awards | Overton Prize (2010)[1] |
| Scientific career | |
| Institutions | |
| Thesis | Molecular propinquity: evolutionary and structural relationships of proteins (1996) |
| Doctoral advisor | Cyrus Chothia |
| Website | compbio |
Brenner gained his Bachelor of Arts in 1992 from Harvard University and Doctor of Philosophy in 1997 from the University of Cambridge for research supervised by Cyrus Chothia.[5][6] He was one of the creators of the Structural Classification of Proteins (SCOP) database[7] while working at the Laboratory of Molecular Biology (LMB) in Cambridge, UK.
As of 2017[update] research in Brenner's laboratory investigates:
- Individual genome interpretation[2]
- The regulation of gene expression by alternative splicing and nonsense-mediated decay of messenger RNA[2]
- Protein function prediction using Bayesian phylogenomics[2]
Awards and honors
In 2010 he was awarded the Overton Prize from the International Society for Computational Biology.[1][8]
- McKay, B. M.; Sansom, C. (2010). "2010 ISCB Overton Prize Awarded to Steven E. Brenner". PLOS Computational Biology. 6 (6): e1000831. Bibcode:2010PLSCB...6E0831M. doi:10.1371/journal.pcbi.1000831. PMC 2891695. PMID 20585610.
- Brenner, Steven (2017). "Brenner Laboratory: Computational Genomics Research Group". compbio.berkeley.edu.
- Stajich, J. E.; Block, D.; Boulez, K.; Brenner, S.; Chervitz, S.; Dagdigian, C.; Fuellen, G.; Gilbert, J.; Korf, I.; Lapp, H.; Lehväslaiho, H.; Matsalla, C.; Mungall, C. J.; Osborne, B. I.; Pocock, M. R.; Schattner, P.; Senger, M.; Stein, L. D.; Stupka, E.; Wilkinson, M. D.; Birney, E. (2002). "The BioPerl Toolkit: Perl Modules for the Life Sciences". Genome Research. 12 (10): 1611–1618. doi:10.1101/gr.361602. PMC 187536. PMID 12368254.
- Brenner, Steven Elliot (1996). Molecular propinquity: evolutionary and structural relationships of proteins. lib.cam.ac.uk (PhD thesis). University of Cambridge. OCLC 879392272. EThOS uk.bl.ethos.596888.
- "About Steven E. Brenner". compbio.berkeley.edu.
- Murzin, A. G.; Brenner, S.; Hubbard, T.; Chothia, C. (1995). "SCOP: A structural classification of proteins database for the investigation of sequences and structures" (PDF). Journal of Molecular Biology. 247 (4): 536–540. doi:10.1016/S0022-2836(05)80134-2. PMID 7723011. Archived from the original (PDF) on 2012-04-26.
