South Dakota Public Universities and Research Center, also known as University Center, is a cooperative higher education delivery system in Sioux Falls, South Dakota. Six universities offer classes at this site: University of South Dakota, Dakota State University, South Dakota State University, Black Hills State University, South Dakota School of Mines and Technology, and Northern State University.^[1] The site, until recently known as "USDSU," has become popular with non-traditional students living in or around Sioux Falls.

In 2006, the South Dakota Board of Regents received authorization to obtain a large area in Sioux Falls to construct a new campus for its Sioux Falls offerings.^[2]

University Center will become a college of the University of South Dakota named "The Community College for Sioux Falls, a branch of USD", a change approved by the Board of Regents in April 2019.^[3]