Setastine
Setastine
Chemical compound
Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis.[1][2]
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Formula | C22H28ClNO |
Molar mass | 357.92 g·mol−1 |
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Pharmacodynamics
Setastine acts as a highly selective H1 receptor antagonist.[3] It has no anticholinergic, antiadrenergic, or antiserotonergic effects.
Pharmacokinetics
Setastine penetrates the blood-brain-barrier poorly so it is only mildly sedating compared to related molecules like diphenhydramine.[3]
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