SEC22B

SEC22B

SEC22B

Protein-coding gene in the species Homo sapiens


Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene.[5][6][7]

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Function

The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.[7] SEC22B has been shown to interact with syntaxin 18.


References

  1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Okumura AJ, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, Nagao K, Nishikawa M, Yoshimura A, Wada I (February 2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system". The Journal of Biological Chemistry. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670.

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