SDK1

SDK1

SDK1

Protein-coding gene in the species Homo sapiens

Sidekick cell adhesion molecule 1 is a protein that in humans is encoded by the SDK1 gene. [5] [6]

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Function

The protein encoded by this gene is a member of the immunoglobulin superfamily.[7] The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016].

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000146555 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000039683 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: Sidekick cell adhesion molecule 1". Retrieved 2018-05-31.
  6. [6]
    "OMIM: SIDEKICK CELL ADHESION MOLECULE 1; SDK1".
  7. [7]
    Yamagata, M (2020). "Structure and Functions of Sidekicks". Frontiers in Molecular Neuroscience. 13: 139. doi:10.3389/fnmol.2020.00139. PMC 7479261. PMID 32982686.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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