Robert A. Holton (born 1944) is an American academic chemist who is known for his work regarding the chemical synthesis for Taxol (known as the Holton Taxol total synthesis), a widely utilized and highly effective anti-cancer drug. He is a professor of chemistry at Florida State University.

Dr. Holton’s research group has accomplished the total synthesis of several natural products. Most notable are prostaglandin F_2α, narwedine, aphidicolin, taxusin, Taxol and hemibrevetoxin B.

Dr. Holton also serves as Chief Scientific Officer, a member of the Board of Directors and co-founder of Taxolog, Inc., as well as President and founder of MDS Research Foundation and Syncure, Inc.

• Bachelors from the University of North Carolina
• Doctorate from Florida State University

• Paclitaxel total synthesis