Pregnanediol_glucuronide

Pregnanediol glucuronide

Pregnanediol glucuronide

Chemical compound

Pregnanediol glucuronide, or 5β-pregnane-3α,20α-diol 3α-glucuronide, is the major metabolite of progesterone and the C3α glucuronide conjugate of pregnanediol (5β-pregnane-3α,20α-diol).[1][2] Approximately 15 to 30% of a parenteral dose of progesterone is metabolized into pregnanediol glucuronide.[1][2] While this specific isomer is referred to as pregnanediol glucuronide and is the most major form, there are actually many possible isomers of the metabolite.[3][4]

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References

  1. [1]
    Josimovich J (11 November 2013). Gynecologic Endocrinology. Springer Science & Business Media. p. 28. ISBN 978-1-4613-2157-6.
  2. [2]
    Etienne-Emile Baulieu; Paul A. Kelly (30 November 1990). Hormones: From Molecules to Disease. Springer Science & Business Media. pp. 401–. ISBN 978-0-412-02791-8.
  3. [3]
    Cupps PT (20 February 1991). Reproduction in Domestic Animals. Elsevier. pp. 101–. ISBN 978-0-08-057109-6.
  4. [4]
    R. Hobkirk (18 January 2018). Steroid Biochemistry. CRC Press. pp. 23–. ISBN 978-1-351-09380-4.



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