Pork–cat_syndrome

Pork–cat syndrome

Pork–cat syndrome

Allergy to pork linked with cat allergy

Pork–cat syndrome is an allergy to pork, usually after adolescence, that is related to cat allergy. Although first described in 1994,[1][2][3] it was first documented in the U.S. by Scott Commins and Thomas Platts-Mills during their research on alpha-gal allergy.[4]

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It is called "pork–cat syndrome" because it is a cross-reactivity where an allergy to cat serum albumin (protein made by a cat's liver)[4] cross-reacts with pork albumin and "can lead to severe or even fatal allergic reactions on occasions when pork is consumed."[3]

In its 1994 description, the subjects studied that were suffering from the allergy were predominantly female, and only 1 out of the 5 observed were male.[5]

See also

References

  1. [1]
    Abreu, Carmo; Gomes, Raquel; Bartolome Borja, Bial-Arístegui; Falcão, Helena; Cunha, Leonor (30 March 2015). "Pork-cat syndrome?". Clin Transl Allergy. 5 (Suppl 3): P164. doi:10.1186/2045-7022-5-S3-P164. PMC 4412402.
  2. [2]
    Warner, Jennifer (6 November 2011). "Pork-Cat Syndrome an Under-Recognized Allergy". WebMD.
  3. [3]
    Posthumus, Jonathon; James, Hayley R; Lane, Charles J; Matos, Luis A; Platts-Mills, Thomas A E; Commins, Scott P (24 March 2017). "Initial Description of Pork-Cat Syndrome in the United States". J Allergy Clin Immunol. 131 (3): 923–5. doi:10.1016/j.jaci.2012.12.665. PMC 3594363. PMID 23352634.
  4. [4]
    Zaraska, Marta (2 December 2013). "Allergic reactions to pork may be prompted by a protein made in the liver of cats". Washington Post. Archived from the original on 25 March 2017. Retrieved 24 March 2017.
  5. [5]
    Nierenberg, Cari (2011-11-11). "Pork-cat syndrome a rare (but real!) allergy". NBC News. Retrieved 2025-06-17.
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