Phosphoserine_transaminase

Phosphoserine transaminase

Phosphoserine transaminase

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Phosphoserine transaminase (EC 2.6.1.52, PSAT, phosphoserine aminotransferase, 3-phosphoserine aminotransferase, hydroxypyruvic phosphate-glutamic transaminase, L-phosphoserine aminotransferase, phosphohydroxypyruvate transaminase, phosphohydroxypyruvic-glutamic transaminase, 3-O-phospho-L-serine:2-oxoglutarate aminotransferase, SerC, PdxC, 3PHP transaminase) is an enzyme with systematic name O-phospho-L-serine:2-oxoglutarate aminotransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

(1) O-phospho-L-serine + 2-oxoglutarate 3-phosphonooxypyruvate + L-glutamate
(2) 4-phosphonooxy-L-threonine + 2-oxoglutarate (3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate

This enzyme is a pyridoxal-phosphate protein.

See also


References

  1. Hirsch H, Greenberg DM (May 1967). "Studies on phosphoserine aminotransferase of sheep brain". The Journal of Biological Chemistry. 242 (9): 2283–7. PMID 6022873.
  2. Pizer LI (December 1963). "The pathway and control of serine biosynthesis in Escherichia coli". The Journal of Biological Chemistry. 238: 3934–44. PMID 14086727.
  3. Drewke C, Klein M, Clade D, Arenz A, Müller R, Leistner E (July 1996). "4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis". FEBS Letters. 390 (2): 179–82. doi:10.1016/0014-5793(96)00652-7. PMID 8706854.

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