OXA1L

OXA1L

OXA1L

Protein-coding gene in the species Homo sapiens

Mitochondrial inner membrane protein OXA1L is a protein that in humans is encoded by the OXA1L gene located on 14q11.2.[5] The C-terminus of this protein interacts with mitochondrial ribosomes and helps insert both mitochondrial and nuclear produced proteins into the inner membrane of the mitochondria.[6][7]

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References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000155463 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000000959 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Molina-Gomes D, Bonnefoy N, Nguyen VC, Viegas-Péquignot E, Rötig A, Dujardin G (1995). "The OXA1L gene that controls cytochrome oxidase assembly maps to the 14q11.2 region of the human genome". Genomics. 30 (2): 396–8. PMID 8586451.
  6. [6]
    Haque ME, Elmore KB, Tripathy A, Koc H, Koc EC, Spremulli LL (2010). "Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes". The Journal of Biological Chemistry. 285 (36): 28353–62. doi:10.1074/jbc.M110.148262. PMC 2934699. PMID 20601428.
  7. [7]
    Haque ME, Spremulli LL, Fecko CJ (2010). "Identification of protein-protein and protein-ribosome interacting regions of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L". The Journal of Biological Chemistry. 285 (45): 34991–8. doi:10.1074/jbc.M110.163808. PMC 2966113. PMID 20739282.
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