ONECUT1

ONECUT1

ONECUT1

Protein-coding gene in the species Homo sapiens

One cut homeobox 1 is a protein that in humans is encoded by the ONECUT1 gene. [5]

Quick Facts Available structures, PDB ...

Function

This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000169856 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000043013 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: One cut homeobox 1". Retrieved 2016-04-13.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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