Nicotine_blue_oxidoreductase

Nicotine blue oxidoreductase

Nicotine blue oxidoreductase

Class of enzymes

Nicotine blue oxidoreductase (EC 1.1.1.328, nboR (gene)) is an enzyme with systematic name 3,3'-bipyridine-2,2',5,5',6,6'-hexol:NADP+ 11-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

3,3'-bipyridine-2,2',5,5',6,6'-hexol + NAD(P)+ (E)-2,2',5,5'-tetrahydroxy-6H,6'H-[3,3'-bipyridinylidene]-6,6'-dione + NAD(P)H + H+
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This enzyme is extracted from bacterium Arthrobacter nicotinovorans.

References

  1. [1]
    Mihasan M, Chiribau CB, Friedrich T, Artenie V, Brandsch R (April 2007). "An NAD(P)H-nicotine blue oxidoreductase is part of the nicotine regulon and may protect Arthrobacter nicotinovorans from oxidative stress during nicotine catabolism". Applied and Environmental Microbiology. 73 (8): 2479–85. doi:10.1128/AEM.02668-06. PMC 1855579. PMID 17293530.
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