Neda Spasojević (16 April 1941 – 16 July 1981) was a Serbian film, television and theater actress. She appeared in more than sixty films from 1964 until her 1981 death from cancer at age 40.

Neda Spasojević was born in the Yugoslav capital city Belgrade the week that the Kingdom of Yugoslavia was invaded by Germany in April 1941. Her father Milorad was a traveling actor. Her mother was an Austrian woman from Vienna named Hilda Lermer, who later adopted the Serbian name Jelena.^[1] Hilda worked as a seamstress for various theaters.

Following a rejection at the Performing Arts Academy in Belgrade, Spasojević took her father's advice about moving to Titograd, SR Montenegro if she wished to pursue a career in acting. She performed in her first show on 23 March 1961.^[2] Spasojević appeared in her first film in 1964, acting alongside Danilo Stojković in Izdajnik.

Spasojević was diagnosed with cancer in early 1981. She died from cancer on 16 July 1981, aged 40, a few weeks after completing her scenes for the film Banović Strahinja.^[3]