NPR3
NPR3
Protein-coding gene in humans
Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR3 gene.[5]
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The family of natriuretic peptides elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[5]
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- Burgess MD, Moore KD, Carter GM, et al. (2009). "C-type natriuretic peptide receptor expression in pancreatic alpha cells". Histochem. Cell Biol. 132 (1): 95–103. doi:10.1007/s00418-009-0591-3. PMID 19352691. S2CID 9116972.
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- Lee JK, Kim HT, Cho SM, et al. (2003). "Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population". J. Hum. Genet. 48 (5): 213–6. doi:10.1007/s10038-003-0011-9. PMID 12768436.
- van den Akker F (2001). "Structural insights into the ligand binding domains of membrane bound guanylyl cyclases and natriuretic peptide receptors". J. Mol. Biol. 311 (5): 923–37. doi:10.1006/jmbi.2001.4922. PMID 11556325.
- He XL, Dukkipati A, Wang X, Garcia KC (2005). "A new paradigm for hormone recognition and allosteric receptor activation revealed from structural studies of NPR-C". Peptides. 26 (6): 1035–43. doi:10.1016/j.peptides.2004.08.035. PMID 15911071. S2CID 28281513.
- NPR2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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