Mycoredoxin

Mycoredoxin

Mycoredoxin

Class of enzymes

Mycoredoxin (EC 1.20.4.3, Mrx1, MrxI) is an enzyme with systematic name arseno-mycothiol:mycoredoxin oxidoreductase.[1] This enzyme catalyses the following chemical reaction

arseno-mycothiol + mycoredoxin arsenite + mycothiol-mycoredoxin disulfide
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Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate.

References

  1. [1]
    Ordóñez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J (May 2009). "Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange". The Journal of Biological Chemistry. 284 (22): 15107–16. doi:10.1074/jbc.m900877200. PMC 2685692. PMID 19286650.
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