MXRA5
MXRA5
Protein-coding gene in the species Homo sapiens
Matrix-remodelling associated 5 is a protein in humans that is encoded by the MXRA5 gene.[3]
Quick Facts Identifiers, Aliases ...
| MXRA5 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | MXRA5, matrix remodeling associated 5 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 300938; HomoloGene: 56704; GeneCards: MXRA5; OMA:MXRA5 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y.[3]
Mutations in this gene have been seen frequently mutated in cases of non-small cell lung carcinoma.[4]
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Matrix-remodelling associated 5". Retrieved 2012-07-24.
- Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, Ma D, Wang Y, You M (Sep 2012). "Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients". Carcinogenesis. 33 (9): 1797–805. doi:10.1093/carcin/bgs210. PMC 3514907. PMID 22696596.
- Chondrogianni N, de C M Simoes D, Franceschi C, Gonos ES (2004). "Cloning of differentially expressed genes in skin fibroblasts from centenarians". Biogerontology. 5 (6): 401–9. doi:10.1007/s10522-004-3188-1. PMID 15609104. S2CID 20230806.
- Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL (Jul 2004). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics. 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218.
- Zou TT, Selaru FM, Xu Y, Shustova V, Yin J, Mori Y, Shibata D, Sato F, Wang S, Olaru A, Deacu E, Liu TC, Abraham JM, Meltzer SJ (Jul 2002). "Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon". Oncogene. 21 (31): 4855–62. doi:10.1038/sj.onc.1205613. PMID 12101425. S2CID 11031338.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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