MEOX1

MEOX1

MEOX1

Protein-coding gene in the species Homo sapiens

Homeobox protein MOX-1 is a protein that in humans is encoded by the MEOX1 gene.[5][6]

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Function

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.[6]

Interactions

MEOX1 has been shown to interact with PAX1[7] and PAX3.[7]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000005102 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000001493 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Futreal PA, Cochran C, Rosenthal J, Miki Y, Swenson J, Hobbs M, Bennett LM, Haugen-Strano A, Marks J, Barrett JC (Jan 1995). "Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture". Hum Mol Genet. 3 (8): 1359–64. doi:10.1093/hmg/3.8.1359. PMID 7987315.
  6. [6]
    "Entrez Gene: MEOX1 mesenchyme homeobox 1".
  7. [7]
    Stamataki D, Kastrinaki M, Mankoo BS, Pachnis V, Karagogeos D (Jun 2001). "Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors". FEBS Lett. 499 (3): 274–8. doi:10.1016/S0014-5793(01)02556-X. PMID 11423130. S2CID 40668112.

Further reading


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