Lumicitabine
Lumicitabine
Chemical compound
Lumicitabine (ALS-8176) is an antiviral drug which was developed as a treatment for respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). It acts as an RNA polymerase inhibitor.[1] While it showed promise in early clinical trials,[2][3] poor results in Phase IIb trials led to it being discontinued from development for treatment of RSV.[4] Research continues to determine whether it may be useful for the treatment of diseases caused by other RNA viruses, and it has been found to show activity against Nipah virus.[5]