LHX6

LHX6

LHX6

Protein-coding gene in the species Homo sapiens

LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.[5][6]

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This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.[6]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000106852 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000026890 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Kimura N, Ueno M, Nakashima K, Taga T (Oct 1999). "A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains". J Biochem. 126 (1): 180–7. doi:10.1093/oxfordjournals.jbchem.a022420. PMID 10393337.
  6. [6]
    "Entrez Gene: LHX6 LIM homeobox 6".

Further reading


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