José Luis Talamillo Huidobro (6 July 1933 – 31 December 1965) was a Spanish cyclist, who competed as a professional from 1957 until 1965.^[1]

Talamillo was a professional from 1956 until his death in 1965. As a road cyclist he won, among other things, the GP Villafranca de Ordizia in 1959 and the Setmana Catalana de Ciclisme in 1965. During the 1961 Vuelta a España, Talamillo held the leader's jersey for two days. He also rode in the 1964 Giro d'Italia, finishing 59th overall.

He was also an accomplished cyclo-cross cyclist, and won the Spanish National Cyclo-cross Championships six times. He also finished 8th in the world championships in 1961.

Talamillo was killed in a traffic accident on the road between Burgos and Logroño on December 31, 1965, leaving behind a wife and two children.^[2][3]