John Bernard Karrs (September 19, 1915 – November 27, 1999) was an American football quarterback who played for the Cleveland Rams in the National Football League (NFL). He played college football at Duquesne University.

He was also one of the first left-handed quarterbacks in the history of the NFL.^[1]

Karrs was a sports coach for several high school teams. He was primarily a coach at New Kenn High for years. In 1944, he was going to accept a new job at Waynesboro High School but ended up backing out shortly after and remaining a coach at Kenn High. However, he was on the hot seat and had an option to either coach at Kenn High, or play a season with the Cleveland Rams. He ended up choosing to play with the Rams and was no longer a coach at Kenn High.^[2][3][4][5]

Despite not playing football for six seasons prior, Karrs signed with the Cleveland Rams in 1944. Playing in all ten games of the season and starting in eight, he threw four completions for 49 yards with a 23-yard pass being his longest of the season. He also rushed seven times for 0 total yards with his longest run being 3 yards.^[6]

Karrs was still on the Rams in the 1945 offseason but got involved in a 2-for-1 trade that put him on the Pittsburgh Steelers two weeks before the preseason began. He did not play an NFL game with the Steelers.^[7]