Reconstruction

In 1933, Architect Stiles O. Clements was hired to build a 45-unit campus with a budget of $353,000.^[7] The "Streamline Modern" building structures were completed in 1935. Ross Dickinson was selected and funded by Federal Art Project to paint four 11 feet by 5.5 foot murals with the theme "The History of Recorded Word". The murals were completed in 1937.^[8]

As of 1936, several notable alumni such as Ralph Bunche, Woody Strode and Samuel R. Browne had graduated from Jefferson High School. All three men were African American, the first of many Jefferson alumni to break racial barriers in the politics of diplomacy, the art of dance, the art of music and the interpretation of sports. Jefferson produced more jazz musicians and composers than any other high school west of the Mississippi.^[9] Many of the musicians were nurtured under the guidance of Samuel R. Browne.

Post-reconstruction

It was in the Los Angeles City High School District until 1961, when it merged into LAUSD.^[10]

Dancers and choreographers

• Alvin Ailey – choreographer and activist; founded the Alvin Ailey American Dance Theater in New York City.^[13]
• Carmen De Lavallade – dancer and actor^[14]

Television and film actors

• Theresa Harris – African American character actress and singer, notable early films include Hold Your Man (1932) starring Jean Harlow and Clark Gable, Baby Face (1933) starring Barbara Stanwyck, and Professional Sweetheart (1933) starring Ginger Rogers
• Woody Strode – African American actor and football player, acted in films including The Ten Commandments, Spartacus, and Posse
• Juanita Moore – actress, fourth African American nominated for an Oscar. Participated in over 50 movies; best known for her role as the mother in the movie Imitation of Life^[15]
• Suzette Harbin – African American actress and dancer in films
• Roland Got – Chinese American actor, best known for The Good Earth (1937)
• Matthew Beard Jr. – African American actor, best known as Stymie in Our Gang (The Little Rascals) shorts

Television and film production and design

• Iwao Takamoto – animator and character designer for Walt Disney Productions and Hanna-Barbera
• John Meehan – art director and production designer

Politicians and judges

• Ralph Bunche – Educator, UN mediator on Palestine and Nobel Peace Prize Winner^[16]
• Thelton Henderson – federal judge in the Northern District of California.^[17]
• Willard H. Murray, Jr. – California State Assembly Member 1988–1996 (District 52); California Institute for the Preservation of Jazz. Current director of the Water Replenishment District 1. Father of Former State Senator Kevin Murray ref: Testimony of Buddy Collette & Marl Young^[18]
• Augustus F. Hawkins – U.S. House of Representatives from California's 21st and 29th district from 1963 to 1991; California assembly from 1935 to 1963^[19]
• David W. Williams – Judge for the United States District Court for the Central District of California; first African American Federal Judge from states west of the Mississippi.^[20]
• William R. Clay – Appointed by Governor Jerry Brown to Superior Court judge in October 1976^[21]
• Earl C. Gay – Los Angeles City Council member, 1933–45
• Mablean Ephriam – prosecuting attorney on television series Divorce Court and Justice with Judge Mablean^[22]

Journalists

• Stanley Crouch – syndicated columnist and novelist best known for his jazz criticism and his 2004 novel Don't the Moon Look Lonesome?^[23]

Composers, songwriters, and music directors

• Roy Ayers – American funk, soul, and jazz composer, vibraphone player, and record producer. ^[24] Nicknamed the "Godfather of Neo-Soul."
• Richard Berry – singer-songwriter, original performer of the rock standard "Louie Louie"^[25]
• Rickey Minor – Emmy-nominated music director, composer, and music producer for shows including The Tonight Show with Jay Leno, American Idol and Don't Forget The Lyrics!
• Barry White – record producer, singer-songwriter; five-time Grammy Award winner. White attended Jefferson for sophomore and junior year.
• Horace Tapscott – Jazz Piano player and composer^[26] Subject of UCLA Jazz Archive called the Horace Tapscott Collection. Creator of "The Pan Afrikan Peoples Arkestra (P.A.P.A.)".
• Jesse Belvin – Songwriter, Singer –^[27] Co-Wrote "Goodnight My Love" used to end Alan Freed Show; co-credited as one of writers of "Earth Angel" made popular by The Penguins.
• Johnny "Guitar" Watson – blues and funk singer-songwriter and guitarist^[28]
• Young Jessie – R&B and jazz singer-songwriter^[29]

Instrumental musicians

• Dexter Gordon – jazz saxophonist known for his music and Starring role in the movie Round Midnight^[30]
• Sonny Criss – jazz saxophone player^[31] – transferred from Jordan High School to Jefferson
• Addison Farmer – jazz bassist^[30]
• Frank Morgan – jazz saxophone player^[32]
• Chico Hamilton – jazz drummer^[30]
• Lee Young – jazz drummer^[30]
• Jack McVea – jazz and Dixieland saxophone player^[30]
• Art Farmer – jazz trumpet player^[30]
• Bill Douglass – jazz drummer^[30]
• Ernie Royal – jazz trumpet player^[30]
• Marshal Royal – jazz saxophone player^[33]
• Lammar Wright, Jr. – jazz trumpet player^[30]
• Vi Redd – jazz saxophone player^[30]
• Jackie Kelson – jazz saxophone player^[30]
• Ginger Smock – concert and jazz violinist^[33]
• Don Cherry – jazz trumpet player^[33]
• Melba Liston – jazz trombone player^[33] – attended Jefferson, but later transferred to Polytechnic High School
• Ed Thigpen – jazz drummer^[24][34]
• Big Jay McNeely – jazz saxophone player^[31] – transferred from Jordan to Jefferson

Singers

• Curtis Williams and Bruce Tate – members of doo-wop group The Penguins^[35]
• Gaynel Hodge, Alex Hodge, and Cornell Gunter – members of musical group The Platters^[36]
• Ray Brewster – member of the groups The Hollywood Flames, The Cadillacs, The Penguins^[35] and The Platters^[37]
• Johnnie Martin – member of the gospel group Mighty Clouds of Joy^[37]
• Etta James – blues singer famous for hit song "At Last"
• Ernie Andrews – jazz and blues singer^[24]
• Merry Clayton – solo musician and backup singer for many artists, including Mick Jagger
• O.C. Smith – jazz singer and minister who performed with Count Basie Orchestra; he recorded the first version of the song ""That's Life" (song)" made famous by Frank Sinatra. He had numerous hit songs in his long career.^[38]
• Mel Walker – lead singer with the Johnny Otis Orchestra^[39]
• Cornell Gunter – R&B singer and member of The Platters and The Coasters. Transferred to Manual Arts his senior year.^[40]
• Jennell Hawkins – R&B and jazz singer^[41]
• Ivie Anderson – jazz singer, performed with Duke Ellington's orchestra between 1931 and 1942
• Richard Berry – singer, songwriter, and musician. Most famous for writing Louie Louie, Berry performed with numerous Los Angeles doo-wop groups including The Flairs. Joseph (Virgil) Johns1960s the Marathons 1983 Barry White's Westwing * Floyd Dixon
• Jose A Lechuga – singer, songwriter and musician. Founder of Regional Mexican Music band Cumbre Norteña

Military

• Theodore Lumpkin Jr. (1919 - 2020) – Tuskegee airman, social worker and businessman^[42]

Visual Artists

• Kerry James Marshall – American artist^[43]

Sports

• Emmett Ashford – first African-American umpire in major league baseball
• Andy Bakjian – National Track and Field Hall of Fame official. Bakjian was a longtime coach at Jefferson.
• Don Bishop – football player for the Dallas Cowboys, Pittsburgh Steelers, and Chicago Bears
• Otis Burrell – 5 time National Champion in the high jump, 1966 NCAA Champion at University of Nevada, Reno, Pan American Games silver medalist.
• Milt Davis – football player for the Baltimore Colts from 1957 to 1961, including winning the 1958 NFL Championship game
• Romeo Doubs – football player for the Green Bay Packers
• Charles Dumas – Olympic high jumper and the first person to clear seven feet. Attended Jefferson in his sophomore and Junior years; transferred to Centennial High School in Compton.
• Joe Kelly – football player for the Cincinnati Bengals
• Edgar Lacey – UCLA basketball player^[44]
• Lee Maye – Major League Baseball player^[45]
• Glenn McDonald – basketball player for the Boston Celtics^[46]
• Bill McGill – NBA basketball player^[47]
• Bernard Quarles – NFL and CFL football player^[48]
• Woody Strode – NFL and CFL football player and decathlete who went on to become an actor^[49]
• Mal Whitfield – Middle-distance runner and Olympic gold medalist^[50]