Hamilton Tiger-Cats

Scarfone had missed his entire fourth year of U Sports eligibility in 2016, but was still drafted in the sixth round, 47th overall, by the Hamilton Tiger-Cats in the 2017 CFL Draft and signed with the team on May 24, 2017.^[4] He began the season on the team's practice roster and was released on July 31, 2017 in order to complete his university playing career.^[5] On December 7, 2017, it was announced that he had re-signed with the Tiger-Cats to a two-year contract.^[6] However, he was released with the final 2018 training camp cuts on June 10, 2018.^[7]

Ottawa Redblacks

On July 3, 2018, Scarfone signed a practice roster agreement with the Ottawa Redblacks, but he was released shortly after on July 8, 2018.^[8][9] He was then re-signed on September 18, 2018, and played in his first career regular season game on October 5, 2018, against the Winnipeg Blue Bombers.^[2][9] He played in four regular season games that year and also played in his first Grey Cup game, but the Redblacks lost the 106th Grey Cup championship to the Calgary Stampeders.^[2]

Scarfone began the 2019 season on the injured list and played in a week 4 game against the Blue Bombers before moving to the practice roster.^[2][10] He returned to the active roster later in the season and recorded his first career reception on August 24, 2021, against the Saskatchewan Roughriders.^[2] He finished the year with seven games played and had three catches for 17 yards.^[2] He became a free agent on February 11, 2020, following the expiration of his contract, but did not sign with any team as the 2020 CFL season was ultimately cancelled.^[11]

BC Lions

On January 27, 2021, it was announced that Scarfone had signed with the BC Lions, re-uniting him with former Redblacks coach, Rick Campbell.^[12] He scored his first career touchdown on a 32-yard reception from Michael Reilly on October 30, 2021, against the Toronto Argonauts in overtime.^[13] On May 3, 2023, Scarfone retired from professional football.^[14]